Life Lines by Dr. Dolittle

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Archive for March 2019

Carnivorous fish are glucose intolerant

Who would have thought that carnivorous fish, like the gilthead sea bream pictured above, and people with diabetes have a lot in common? These fish are glucose intolerant, meaning they are not able to use glucose for energy very well. When these fish are given carbohydrates, their blood sugar increases as does their ability to produce fats through lipogenesis. The purpose of this increase may be to store the excess […]

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Sleep = better DNA repair

I read an interesting article published in┬áNature Communications┬áthat described how zebrafish larvae need sleep to help fix damaged DNA that accumulates in their brains during the day. The researchers engineered zebrafish larvae to have fluorescent chromosomes in a single neuron, which allowed them to observe double-strand breaks in the DNA build-up during wakefulness. In contrast, chromosome activity necessary for repair increased when the animals were sleeping. If the researchers disrupted […]

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