Life Lines by Dr. Dolittle

Sponsored by the American Physiological Society

Nature’s Solutions

Your dog’s internal compass

Apparently pooping is not the only thing dogs do that align with the Earth’s magnetic field. Hunting dogs are kind of like migratory birds in their ability to roam and find their way back to the same spot, while relying on the Earth’s magnetic field. In a new study published in eLife, the same researchers that discovered how dogs prefer to poop found that hunting dogs appear to use the […]

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Researchers discover cause of hearing loss in an underground dweller

Naked mole rats are rather extreme animals in many ways. As underground dwellers, they live in chronically hypoxic environments and are blind. These animals also age more slowly than other mammals and are resistant to developing cancer even though they are long-lived. Did you also know, they are hard of hearing? In a new study published in Current Biology, researchers have discovered the cause of their hearing loss. The inner […]

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Researchers explore why wild canids live longer than domestic dogs and why size matters

Ever wonder why some breeds of dogs live longer than others? Or why wild canids, such as gray wolves, live longer than similar sized domesticated dogs (20.6 vs 10-12 years)? Drs. Ana Jimenez (Colgate University, New York) and Dr. Cynthia Downs (State University of New York, Syracuse) teamed up to examine a common marker of aging in animals – oxidative stress. Oxidative stress happens when there is a build-up of […]

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It’s shark week!! Let’s talk about the spiny dogfish

I am so excited it is finally Shark Week on Discovery Channel! I look forward to this week every year. In honor of Shark Week, I found a neat study published in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology examining the rectal gland of the spiny dogfish shark (Squalus acanthias). This gland is very important as it allows the animals to get rid of salt (sodium […]

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Llamas to the rescue?

A couple years back, we talked about how nanobodies created by camelids, such as alpacas and llamas, may lead to the discovery of new disease-fighting drugs. Aptly named, nanobodies are tiny pieces of antibodies that can bind to target proteins more easily than larger antibodies. Researchers in labs around the world are now exploring llama nanobodies for the treatment of Covid-19. Check out the video below released this month by […]

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Cholesterol levels in tissues change during hypoxia in naked mole rats

Naked mole rats are rather famous from a physiological perspective for their amazing ability to live in hypoxic conditions. They do so in part by reducing their metabolic rate. In fact, researchers at the University of Ottawa in Canada showed that reducing environmental oxygen levels to 11% resulted in a 34% decrease in the animal’s metabolic rate. Studies of hypoxia-tolerant goldfish show that the animals respond to hypoxia challenges by […]

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Exploring how temperature impacts the characteristics of animals

We are delighted to speak with Dr. Casey Mueller who is currently an Assistant Professor at California State University San Marcos. Dr. Mueller is a member of the Comparative and Evolutionary Physiology section of the American Physiological Society and was scheduled to present her research at the 2020 Experimental Biology conference last month. Unfortunately, the conference was cancelled due to Covid-19. Her researchappears in the May issue of the FASEB […]

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What’s the buzz about bees?

We are excited to share the following interview with Dr. Lizzette Cambron, an NSF Graduate Fellow working in Dr. Kendra Greenlee’s laboratory at North Dakota State University. Dr. Cambron was scheduled to present her research at the 2020 Experimental Biology conference last month in a Comparative and Evolutionary Physiology session hosted by the American Physiological Society. As with many conferences, the meeting was cancelled due to Covid-19.  She has agreed […]

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Physiology of diving animals: how do they deal with hypoxia?

Dr. Jose Pablo Vazquez-Medina (pictured at right), a comparative physiologist at the University of California – Berkeley, was scheduled to present several ongoing studies from his lab at the Experimental Biology conference last month. Dr. Vazquez-Medina is a member of the Comparative and Evolutionary Physiology section of the American Physiological Society. Although the conference was cancelled due to Covid-19, Dr. Vazquez-Medina has agreed to share his research with us.   […]

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Dolphins can develop similar neurological diseases as humans

I am pretty sure most people would agree that dolphins are pretty smart. But did you know that they may develop similar neurological conditions as humans? I read an interesting article published in Drug Target Review exploring how dolphins that have washed up on beaches may help us understand neurological diseases like Alzheimer’s as well as responses to viral infections. For example, Dolphin morbillivirus (DMV) is a virus similar to […]

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