Life Lines by Dr. Dolittle

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Nature’s Solutions

New study discovers how zebrafish mend a broken heart

A new study has helped unravel the mystery explaining how zebrafish regenerate a broken heart. Their findings, published in Nature Genetics, reveal how these amazing little fish can regrow up to 20% of their heart in only 2 months following an injury. This regeneration is driven by signals released from special cells called fibroblasts. When the heart of zebrafish is injured by a stimulus that mimics a heart attack (using […]

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Buoyancy and Balance

Existing species of coelacanths (pictured above) are descendants of a group of fish that existed about 410 million years ago, during the early Devonian period. They can be found in the Western Indian Ocean off the coast of Indonesia. These fish are really interesting because they have very low metabolic rates. In fact, their metabolism is among the lowest of any other existing vertebrate. Even sloths are jealous of their […]

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Turning up the heat

There are several ways to stay warm on a cold day. If you are human, you can turn up the heat in your home, put on a sweater, snuggle, and even produce body heat through shivering as well as non-shivering metabolic pathways – although the ability to produce heat metabolically typically declines with aging. If you are a small mammal, turning up the heat or putting on a sweater are […]

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EB 2022: Seals, seals, and more seals

Several posters at EB 2022 in Philadelphia this month were focused on understanding the remarkable physiology of diving seals. Although we may think of the image below when we picture seals, they really are quite the athletes in water. Kaitlin Allen (a graduate student working in the laboratory of Dr. José Pablo Vázquez-Medina at the University of California Berkeley) presented her research on Northern elephant seals and how these animals […]

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EB2022: Facing Oxygen Challenges

I learned a lot about how animals adapt to changing environmental oxygen levels in the Experimental Biology symposium on “Functional Integration across the Oxygen Cascade in the Face of Challenging Environments.” Here is what I learned… The first presenter, Dr. Lara do Amaral-Silva (postdoctoral fellow at the University of North Carolina at Greensboro working with Dr. Joseph (Joe) Santin), spoke about her research on adaptations in the bullfrog “super-brain” that […]

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Stranger than science fiction: treefrogs that freeze and live to tell the story

Today we have a guest blog written by Elizabeth Evans (pictured above), a graduate student at the University of Dayton working in the laboratory of Dr. Carissa Krane. She presented her research on freeze tolerance today at the 2022 Experimental Biology conference in Philadelphia. She wrote the award-winning blog entry below which earned the 2022 Dr. Dolittle Travel Award to attend the conference. Congratulations Elizabeth!! Stranger than science fiction: treefrogs […]

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2022 August Krogh Distinguished Lecturer, Dr. Patricia Schulte

Each year, the Comparative and Evolutionary Physiology section of the American Physiological Society presents their highest award, the August Krogh Distinguished Lecture, to a comparative physiologist who “has made major and meritorious contributions” to the field. Dr. August Krogh (1874-1949) was a physiologist who won the Nobel Prize in Physiology or Medicine in 1920. He was very interested in zoology and joined the University of Copenhagen as an Associate Professor […]

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Hibernation slows down aging

I don’t know about you, but when I see an article claiming to be able to explain “The Biology of Beauty Sleep”, I simply have to read it. Clicking on the title brought me to a news article from the journal Nature Ecology & Evolution that featured a recent study examining the idea of how sleep impacts aging. The burning question of course is whether or not there is any […]

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Tips to avoiding blood clots and improving blood storage for transfusions

Hibernating mammals are amazing! How in the world do they prevent blood clots when they not only reduce their body temperature but also their blood flow during hibernation? That question is precisely what a new study published in Physiological Genomics examined.   Typically, cold temperatures are known to activate the process of blood clotting by stimulating platelets. Platelets are sticky cells without a nucleus that circulate in the blood. When […]

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