Life Lines by Dr. Dolittle

Sponsored by the American Physiological Society

Archive for February 2021

Towards developing treatments for inflammation

Neutrophils are specialized immune cells that becomes activated in response to foreign particles or microorganisms. Think of them like security guards in your body. As they travel through the blood, their job is to detect and get rid of invading microorganisms. They also help spark inflammation responses to infections. For these reasons, they are known to help maintain homeostasis in the body, but they can also play roles in disease […]

Continue Reading →

New research working towards preventing and treating necrotizing enterocolitis in premature babies

Necrotizing enterocolitis is an inflammatory disease of the intestines. New research suggests that premature babies are at risk of necrotizing enterocolitis in part because they have low levels of arachidonic and docosahexanoic acids in their gut, which regulate inflammation. Doctors routinely administer nutritional supplements to premature babies via an intravenous (i.v.) route until the gastrointestinal tract develops and the babies are able to process oral foods. This parenteral nutrition helps […]

Continue Reading →

Frogs are teaching researchers about autism

Dr. Helen Willsey at the University of California San Francisco is seeking to understand how autism develops with the help of frogs. Because frogs produce thousands of embryos at the same time, she is able to quickly study the effects of many different gene alterations in the offspring. While the embryos are at the two-cell stage of development, her laboratory alters genes in just one of the cells using CRISPR-Cas9 […]

Continue Reading →

Metabolic costs of reproduction, eating, and increasing temperatures

Planarians are rather cute little flatworms, although they tend to wreak havoc in fish tanks. Researchers have long been fascinated by their ability to regenerate body parts when injured with the help of adult stem cells. More recently, they have gained attention for their ability to survive long periods of time without eating by “degrowing”, i.e. getting smaller but still keeping their shape and functions intact. I would shrink too […]

Continue Reading →