Life Lines by Dr. Dolittle

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Archive for January 2022

Regenerating Lost Limbs

When most animals lose a limb, it is lost forever. However, several animals such as salamanders and lizards are known to regrow lost limbs. In a new study, researchers have been able to regenerate a lost limb in adult African clawed frogs, Xenopus laevis, which is a species that normally does not regrow lost limbs. Regeneration was achieved by applying a wearable silicon bioreactor cap called a BioDome containing a […]

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More on the uniqueness of humans when it comes to heart disease…

With Valentine’s Day just around the corner, heart-themed items seem to be everywhere. It is no surprise that I started thinking more and more about how humans are unique from other animals when it comes to heart disease. In my last entry, we talked about a few genetic variants that protect some humans from heart disease as well as the observation that many carnivores do not develop atherosclerosis, even when […]

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Preventing Atherosclerosis

Researchers have identified variants in the B4GALT1 gene of Amish people that are associated with low levels of LDL (i.e. “bad”) cholesterol and fibrinogen, a gene involved in blood clotting. In fact, people with variants in this gene are 35% less likely to be diagnosed with heart disease. When the variant was expressed in mice, the animals had similar decreases in LDL cholesterol and fibrinogen. Researchers are hoping to create […]

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Surviving environmental challenges

Red tides happen when dinoflagellate algae populations increase and turn the water a shade of red due their red pigments. These algae consume oxygen in the water and release carbon dioxide and other acidic products that make the surrounding water acidic and hypoxic. These events are becoming more common with climate change. In fact, the most recent event off the coast of Sothern California occurred in 2020 and resulted in […]

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Combating kidney stones

If you have ever had a pet with kidney stones, you know that diet can be a major contributing factor to their formation. This is why veterinarians often recommend providing animals with foods higher in water content and switching to a diet that promotes a healthy urine pH (not too basic, not too acidic).   Did you know that bottlenose dolphins can develop kidney stones too? The particular kind of […]

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