Dr. Graham Scott (McMaster University) presented intriguing research at the American Physiology Summit earlier this month in Long Beach, CA. His laboratory has been examining a potential link between the gut microbiome and the ability for deer mice to help regulate body temperature. Deer mice live in high elevations where atmospheric oxygen levels are low. This presents a physiological challenge as they have to use a lot of energy to […]
In a new study published in The Journal of Neuroscience and presented at the American Physiology Summit earlier this month, graduate student Nikolaus Bueschke, postdoctoral fellow Dr. Lara Amaral-Silva and Dr. Joseph Santin (University of Missouri, Columbia) together with researchers Min Hu and Alvaro Alvarez (University of North Carolina at Greensboro), explored how bullfrogs (Lithobates catesbeianus) emerging from hibernation tolerate hypoxia while they kickstart physiological functions in ice-covered ponds. This […]
Hibernation allows animals to reduce their energy needs during winter, when food may be scarce and high amounts of energy would be required to maintain body temperature. These animals prepare for winter by storing body fat that can be used as fuel during hibernation. Skeletal muscles in particular have high energy needs as they make up nearly half of an animal’s body mass. They also play important roles in regulating […]
The lifespan of a red blood cell (RBC) in a healthy human is about 120 days and approximately 200 billion red blood cells (RBCs) are replaced every day in healthy adult humans! Most (80%) of the carbon monoxide produced in humans comes from the breakdown of heme which is released when these red blood cells (RBC) are broken down through normal homeostatic processes. Sickle cell anemia shortens the lifespan of […]
Freezing temperatures are no match for alligators. Recent images emerging from Texas and North Carolina show frozen ponds and swamps dotted with alligators. Similar to animals that experience torpor, alligators are able to reduce their metabolism and heart rate to as little as three beats per minute to survive freezing temperatures. This torpor-like state is called brumation. Poking their snouts above the ice before it freezes, allows them to continue […]
The Arizona Physiological Society held their 16th annual meeting this past weekend at Midwestern University in Glendale, Arizona. The Arizona Established Scientist Keynote Speaker was Dr. Christopher Glembotski, Professor of Internal Medicine and Director of the Translational Cardiovascular Research Center at the University of Arizona, Phoenix campus. Ischemic diseases, such as strokes and heart attacks, disrupt the normal functioning of the endoplasmic reticulum, which alters protein production and folding. His […]
The Midlands Society of Physiological Sciences held their annual conference on October 21st at the University of Nebraska Medical Center. The Keynote Lecture was given by Dr. Manolis Kellis, Professor at Massachusetts Institute of Technology. He spoke about the use of artificial intelligence approaches to examine how fly and human genes are regulated. Other highlights: Anuj Singh (University of Nebraska Medical Center): Opioid use is a major healthcare concern and […]
The Ohio Physiological Society met October 6-7th at The University of Toledo located in Toledo, OH. True to the name of this year’s conference, the Keynote address was given by Dr. Joseph Wu, Director of the Stanford Cardiovascular Institute and current president of the American Heart Association. His research focuses on congenital heart disease in adults as well as cardiovascular imaging. His most recent clinical trials involve testing bone-derived stem […]
Cope’s gray treefrogs, Dryophytes chrysoscelis, are remarkable animals that can actually survive being frozen…multiple times each year. In fact, these animals live in an environment in which temperatures commonly dip below freezing. When temperatures drop, up to 65% of their body water literally freezes. In anticipation of freezing temperatures, they begin to accumulate cryoprotectant chemicals during the fall to help protect their organs. Until now, the effects of repeated cycles […]
While studies have shown that Tibetans protect their tissues from damage caused by low oxygen levels at high altitude, other studies have shown that people adapted to life in the Andes mountains have genetic variations that protect their hearts. In a recent study presented at the 2023 American Physiology Summit, scientists discovered that 68% of Andean highlanders carry a single nucleotide variation in the gene responsible for encoding the protein […]
Life Lines by Dr. Dolittle 