Life Lines by Dr. Dolittle

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Dogs and humans have a lot in common when it comes to brain tumors

The most common type of naturally occurring brain tumor in humans and their feline as well as canine companions are meningiomas. The most aggressive form in humans is Meningioma C (MenG C). Unfortunately, there is currently no treatment available for MenG C and tumors often return even after radiation and surgery. Researchers were curious whether canine meningiomas were similar to human MenG C. In a newly published study, appearing in […]

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Gray wolves living within the Chernobyl Exclusion Zone develop cancer resilience

Like humans, dogs are at risk of spontaneously developing cancer as they age. In fact, cancer is the leading cause of death for dogs (Gardner et al., 2016). Research suggests that dogs may better model cancer than rodents because the disease progression is similar to humans including involvement of the immune system, molecular pathways, variations between animals, tumor resistance to chemotherapy, and metastasis (Gardner et al., 2016). Thus, understanding and […]

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It’s all about the butt microbiome

While the gut microbiome has been gaining a lot of attention for its potential role in health and disease, it appears that the butt microbiome is important in feline communication. How many times have you seen cats sniffing each other? Brave researchers at the University of California at Davis explored this hidden side of cat communication and published their findings in Scientific Reports. The researchers identified both the bacterial species […]

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What do you get when you cross a dog and a fox?

Answer: A really cool hybrid (above). In 2021, someone brought a “dog” to a rehabilitation center in Vacaria, Brazil that had been injured by a car. However, upon further examination, they discovered she wasn’t a dog. She also preferred to eat rats over boring dog food. Disruptions of natural habitats in South America have led to increasing interactions between wild canids and domestic dogs. In this case, scientists discovered the […]

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Understanding aging in dogs may help us all live longer

“Dog Aging Project” was founded by aging researchers Drs. Matt Kaeberlein and Daniel Promislow (University of Washington) along with Kate Creevy who is currently the Chief Veterinary Officer. The goal of the project is to examine how the environment affects healthy aging and longevity in dogs and to test anti-aging treatments. This research has the potential to also impact how we understand environmental risk factors for aging in humans as […]

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One reason why fish and mammals lose their appetite during stress

I don’t know about you, but sometimes I lose my appetite when I am really stressed. The endocrine system is responsible for controlling our stress responses and involves three main endocrine glands – the hypothalamus, pituitary, and adrenal gland. Hence, the stress pathway is often referred to as the “HPA axis”. When we are stressed, the hypothalamus releases a hormone called corticotropin releasing factor (CRF), which triggers the release of […]

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Goldfish learn how to drive and target similar visual cues as humans

Researchers at Ben-Gurion University of the Negev constructed a tank on wheels that goldfish actually learned how to “drive”. Using cameras, the “car” was able to move in the direction the fish swam. They then tested whether the fish could purposefully navigate the car towards a target and observed that the fish could indeed swim towards a target in return for a treat, of course. In a prior study, the […]

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Humans do it, cats do it, dogs do it…why can’t rodents or rabbits do it?

Did you know that rodents and rabbits are not able to vomit? This was certainly news to me. So, I had to find out more… First, let’s talk about the difference between retching and vomiting. During retching (or dry heaves), the diaphragm and abdominal muscles contract, which helps increase pressure within the stomach (and prepare the contents for expulsion). Vomiting also involves contractions of the diaphragm, abdominal as well as […]

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EB 2022: Modeling human diseases and healthy aging

I sat through a very interesting session at this year’s Experimental Biology conference called, “The Power of Comparative Models for Accelerating Translational Healthspan Research: Underutilized Lab Animals, Companion Pets, Old World Monkeys, and Pumas.” While the title seems to capture the general idea of the symposium, I thought I would share a bit more information about the presenters and their exciting research. Dr. Karyn Hamilton from Colorado State University presented […]

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Arizona Physiological Society’s annual conference: Part 2

Arizona’s physiologists met in October to talk about Rocky Mountain Spotted Fever, urbanization, the evolution of walking and vocalizations, snow leopards, and diet. Here are the highlights… Oral Presentations: Graduate student Luke Endicott from the Arizona College of Medicine at Midwestern University, working with R. Potter and Dr. C.R. Olson presented their research exploring how zebra finches learn to sing and the importance of vitamin A in this process. Does […]

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