Mosquitoes suck! (and pee, too)

As if sucking our blood wasn’t bad enough, I was horrified to learn that mosquitoes also pee on us while they’re drinking. Yuck! In this time machine, we revisit a 1987 paper published in Physiology that explains why. Female mosquitoes require blood meals to obtain the proteins necessary for egg production. During a single meal, they can consume up to twice their body mass in blood. That’s like a 150-pound […]

Continue Reading →

Red, White, and Bison: Celebrating Freedom and National Bison Month

Happy 4th of July! What a perfect time to also honor National Bison Month! This month, we celebrate an icon of the American landscape. Bison are incredible animals, not just for their symbolic significance but also for their remarkable adaptations to extreme environments. As highlighted by the National Park Service’s Bison Bellows, their resilience in the face of brutal winters is extraordinary. Bison are uniquely adapted to harsh winter conditions […]

Continue Reading →

Time Machine: Is lactic acid really to blame for muscle fatigue?

Have you ever experienced muscle fatigue? You know the feeling where your muscles start to burn and no matter how hard you try, you simply cannot summon any more strength? It is often assumed that the burning sensation associated with muscle fatigue is due to lactic acid building up in the muscles. But is that the full story? In this time machine post, we examine the science behind muscle fatigue […]

Continue Reading →

Ocean oddity: how teleost fish stay hydrated in saltwater

It may sound strange to hear that saltwater fish need to stay hydrated. After all, they live in water. However, a review published in Physiology describes how nearly all saltwater fish are thought to have evolved from freshwater ancestors, and many maintain similar levels of salt in their blood as freshwater animals. Living in a saltwater environment means that these fish have to find a way to get rid of […]

Continue Reading →

Muscle adaptations to endurance exercise

Happy Pigeon Appreciation Day! Okay, I know it sounds strange to celebrate pigeons – the animal best known for gathering in large numbers, causing a raucous, as well as perching and pooping on just about everything. For just a moment though, I would like to consider the unique athletic attributes of these popcorn and park loving birds vs humans engaged in endurance exercise. Have you ever heard of pigeon racing […]

Continue Reading →

Time Machine: Keeping it hot…or not

In todays’ Time Machine, we are taking a look back at a paper written by Dr. Henry Gray Barbour during his time in the Department of Pharmacology at Yale University School of Medicine. Published in Physiological Reviews in 1921, his paper examined how body heat is regulated in various species. In this review, Dr. Barbour explains that water is the best medium for conducting heat throughout the body. This is […]

Continue Reading →

Discovered by accident: Queen bumblebees can hibernate underwater!

Dr. Sabrina Rondeau, a postdoctoral fellow at the University of Ottawa, made a surprising discovery that has created quite the buzz. While checking on queen bumblebees hibernating in the refrigerator, she noticed that condensation had formed inside some of the containers housing the queen bumblebees. Interestingly, the bees survived the ordeal. Intrigued by how exposure to water might affect queen bees during hibernation, Dr. Rondeau conducted an experiment in Bombus […]

Continue Reading →

“Hummingbirds of the Night”

A reference to nectar-feeding bats as “hummingbirds of the night” in a presentation at the 2025 American Physiology Summit in Baltimore last month caught my eye. What an appropriate nickname for bats that can have blood sugar levels exceeding 750 mg/dl after a meal! Sure, a hummingbird would think this was normal, but for a human these levels would warrant a trip to the emergency room. New research shared by […]

Continue Reading →

The electrophysiology of sudden cardiac death in high-performance athletes

Humans and racehorses have something in common when it comes to risk of sudden cardiac death. In fact, sudden cardiac death is the 2nd most common cause of death during exercise among these athletes. Although rare, it typically affects young, seemingly healthy individuals. Research suggests that exercise itself is not to blame, but rather an underlying predisposition for irregular heart rates that exercise uncovers. The most common inherited causes of […]

Continue Reading →

Some like it hot: Genetic twists in warm hibernation

Hibernation was also a hot…I mean warm…topic at the American Physiology Summit last month in Baltimore, MD. Thomas Crippen presented research conducted with team members Dr. Dylan Barth, Zac Carlson, Dr. Frank van Breukelen, and Dr. Allyson Hindle at the University of Nevada, Las Vegas. Their study focused on golden-mantled ground squirrels, Callospermophilus lateralis, which are remarkable even among hibernators. These squirrels can enter torpor across a range of environmental […]

Continue Reading →