Time Machine: Multitasking Melatonin

Back in 2012, the American Physiological Society put together an amazing list of the top ten articles cited in each of their journals every quarter of a century in honor of their 125th anniversary. In looking through the website this week, I stumbled upon this collection and was reminded about the amazing early foundational work and excellence in physiology research found within this body of work. So, I’d like to […]

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Out of the cave and into the lab: Why it’s time to go bat-ty in research!

As we talked about previously, bats are amazing mammals. Like Batman, they fly and fight off many potential enemies. – albeit their enemies are typically microscopic as opposed to cartoon-like super-villains. Their remarkable resilience to cancers and various pathogens has attracted the attention of scientists and even resulted in the formation of the Bat1K Consortium aimed at sequencing the genome of various species of bats to search for clues that […]

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Stress is contagious, even for dogs

Stress can make people pretty stinky. Humans have two main kinds of sweat glands. The eccrine glands produce sweat that we associate with exercise or warm weather – thin, watery and mostly odorless. We can thank apocrine glands for responding to stress by producing a thick fluid containing fats and proteins that skin bacteria love to digest. The result: stinky compounds somewhat reminiscent of vinegar or leeks. While humans may […]

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Tiny Devils Hole pupfish make a big comeback

Devils Hole pupfish (Cyprinodon diabolis) are a tiny critically endangered fish that live in a pond in just one limestone cave, known as Devils Hole, in Death Valley, Nevada. In fact, their habitat is the smallest known for a vertebrate. Biologists from the Nevada Department of Wildlife, US Fish and Wildlife Service and the National Park Service have been painstakingly counting these tiny fish twice a year. Counting these fish […]

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Researchers discover how hibernating ground squirrels protect their cells from self-destruction

Programmed cell death, otherwise known as apoptosis, is an important physiological process that allows the body to get rid of cells that are no longer needed or are damaged. These functions help foster normal growth and development as well as prevent cancer. Apoptosis is a highly regulated process that involves various caspase enzymes, with caspase-3 being among the “executioner” enzymes responsible for the final stages of apoptosis and ultimate cellular […]

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It’s all about the glucose

A lack of available food resources drives many species to forego reproduction until conditions improve. In other words, there is a trade-off between reproduction and foraging. This link was the subject of a recent study of Drosophila melanogaster published in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology.   To examine the link, researchers placed fed or food-deprived Drosophila into a testing arena with another animal of […]

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New study provides more insight into the physiology of elite divers

If the Olympics allowed marine mammals to compete, they would dominate free diving competitions in terms of breath holding duration and extreme physiology. Marine mammals also have adaptations that help prevent tissue damage from the lack of oxygen during such dives. For example, Weddell and northern elephant seals store large amounts of oxygen in their blood and muscles, thanks to abundant hemoglobin, which permits them to hold their breath for […]

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Even shy animals find overcrowded conditions more stressful than bold animals

In a newly published study in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology, researchers examined the relationship between behavioral and physiological responses to stress in a model organism, zebrafish. Following a series of behavioral tests, the fish were classified as either shy or bold and were then exposed to either overcrowded (32 fish per liter) or control conditions (1.6 fish per liter). After 10 days, the […]

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Researchers discover a biological signature that can be used to predict the maximum lifespan of mammals

With the multitude of anti-aging products on the market today, it may be hard to believe that humans are one of the longest-living mammals. Why organisms age and how to slow down this process, or at least ensure that organisms stay healthy as they age, has been on the minds of many researchers over the years. Now, an international team of researchers called the Mammalian Methylation Consortium, led by Dr. […]

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Advancements in veterinary wound healing

Antibiotic-resistant infections are a global concern for both humans and animals. A recent study published in Veterinary Quarterly tested a new way to treat an antibiotic-resistant Pseudomonas aeruginosa wound infection in a Siamese cat, known as “Squeaks”. Squeaks had acquired the infection following multiple surgeries that aimed to treat the cat for injuries after a severe fall from a high-rise. In this study, the veterinary team created a viral phage […]

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