Life Lines by Dr. Dolittle

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Tag Archive for ‘American Physiological Society’

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What dolphins can teach us about healthy aging

The risk of developing cardiovascular disease increases with aging as arteries can become increasingly stiff and the inner lining, called the endothelium, can become dysfunctional. Postdoctoral fellow Dr. Yara Bernaldo De Quiros Miranda (University of Las Palmas de Gran Canaria) is interested in understanding how bottlenose dolphins, Tursiops truncatus, protect their cardiovascular system during aging. She is currently a visiting scholar at the University of Colorado at Boulder where she […]

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Speaking of hypoxia tolerance…

Amy Klink, a graduate student working in the laboratory of Dr. Allyson Hindle at the University of Nevada, Las Vegas, has been studying hypoxia tolerance of Weddell seals. These remarkable animals can hold their breath for 90 minutes and dive as deep as 900 meters! During such long and deep dives, these seals slow down their heart rate and constrict blood vessels in visceral as well as peripheral organs. As […]

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What sea turtles can teach us about hypoxia tolerance

Imagine being able to explore the Earth’s oceans without needing special oxygen equipment. Loggerhead sea turtles have this ability and can actually hold their breath for up to 7 hours! According to the Guiness Book of World Records, Budimir Šobat from Croatia set the record in 2021 for being able to hold his breath for 24 minutes and 37.36 seconds underwater. While quite remarkable, he would need to hold his […]

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Flexible hypoxia tolerance in frogs

In a new study published in The Journal of Neuroscience and presented at the American Physiology Summit earlier this month, graduate student Nikolaus Bueschke, postdoctoral fellow Dr. Lara Amaral-Silva and Dr. Joseph Santin (University of Missouri, Columbia) together with researchers Min Hu and Alvaro Alvarez (University of North Carolina at Greensboro), explored how bullfrogs (Lithobates catesbeianus) emerging from hibernation tolerate hypoxia while they kickstart physiological functions in ice-covered ponds. This […]

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2024 August Krogh Award Recipient: Dr. Martin Grosell

Congratulations to Dr. Martin Grosell, recipient of the 2024 August Krogh Distinguished Lectureship from the Comparative and Evolutionary Physiology section of the American Physiological Society! Dr. Grosell is professor and chair of the Department of Marine Biology and Ecology at the University of Miami Rosenstiel School of Marine, Atmospheric, and Earth Science in Florida. The Krogh award is sponsored by Novo Nordisk Foundation and is awarded to a member of […]

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Guest Blog: Fasting as a strategy to build athletic diving capacity

Kaitlin Allen is a graduate student at the University of California, Berkeley where she studies the physiology of elephant seals in the laboratory of Dr. José Pablo Vázquez-Medina. She received the 2024 Dr. Dolittle Travel Award from the Comparative and Evolutionary Physiology section of the American Physiological Society to attend the 2024 American Physiology Summit in Long Beach, CA (April 4-7). Kaitlin prepared this award-winning guest blog entry to describe […]

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Let’s stop lactate-shaming

As wisely stated in an editorial by Dr. George Brooks, UC Berkeley (2001), “Nature is smarter, and things are more complex than we mortals imagine.” Sure lactate is produced during exercise and is often blamed for causing muscles to fatigue, but there is much more to the story. In fact, research has shown that lactate plays many important physiological roles in the body such as serving as a metabolic fuel […]

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Roses are red, violets are blue, beluga whales and dolphins have higher carbon monoxide than you

The lifespan of a red blood cell (RBC) in a healthy human is about 120 days and approximately 200 billion red blood cells (RBCs) are replaced every day in healthy adult humans! Most (80%) of the carbon monoxide produced in humans comes from the breakdown of heme which is released when these red blood cells (RBC) are broken down through normal homeostatic processes. Sickle cell anemia shortens the lifespan of […]

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Study examines how statin exposure affects cholesterol metabolism in fish

Despite its bad reputation, cholesterol serves many important functions in the body. It is necessary for normal cell structure and is a precursor for the formation of steroid hormones, vitamin D, and bile acids. Too much “bad” cholesterol (LDL), however, can promote cardiovascular diseases and nonalcoholic fatty liver disease. For this reason, many animals tightly regulate cholesterol levels in the body. Fish often have higher cholesterol levels than humans and […]

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Is it just a fluke?

Lung flukes, Hematoloechus sp., are pesky little parasites. Up to 89 species of lung flukes have been identified to date. Their life cycle includes two intermediate hosts, the first of which are freshwater snails that swallow fluke eggs. After ingestion, the eggs hatch and produce a larval form of the parasite called cercaria, which are shed from the snails and taken up by damselflies or dragonflies. These are quite the […]

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