Life Lines by Dr. Dolittle

Sponsored by the American Physiological Society

Tag Archive for ‘Atherosclerosis’

Causes and consequences of stiff arteries

In a new review article published in Physiology, researchers speculate that arterial stiffness in middle-aged adults may actually be the body’s way of trying to compensate for widening of the blood vessel walls as we age. But that benefit turns into a risk with aging as it increases the flow of blood into organs like the brain, kidney, and heart and damages the small blood vessels in those organs. Interestingly, […]

Continue Reading →

More on the uniqueness of humans when it comes to heart disease…

With Valentine’s Day just around the corner, heart-themed items seem to be everywhere. It is no surprise that I started thinking more and more about how humans are unique from other animals when it comes to heart disease. In my last entry, we talked about a few genetic variants that protect some humans from heart disease as well as the observation that many carnivores do not develop atherosclerosis, even when […]

Continue Reading →

Preventing Atherosclerosis

Researchers have identified variants in the B4GALT1 gene of Amish people that are associated with low levels of LDL (i.e. “bad”) cholesterol and fibrinogen, a gene involved in blood clotting. In fact, people with variants in this gene are 35% less likely to be diagnosed with heart disease. When the variant was expressed in mice, the animals had similar decreases in LDL cholesterol and fibrinogen. Researchers are hoping to create […]

Continue Reading →

Anti-aging Vaccine

Scientists have created a vaccine that slows aging, at least in mice. Their findings were recently published in Nature Aging. As we age, the ability for the body to get rid of damaged cells declines, which can lead to inflammation and a host of diseases like cancer, Alzheimer’s disease, as well as atherosclerosis. The vaccine works by triggering the immune system to create antibodies against a specific protein associated with […]

Continue Reading →

Bee sting therapy – revisited

Bee sting therapy has been getting a lot of buzz lately. I have received a lot of questions about applications of so-called apitherapy to conditions other than multiple sclerosis, which we discussed awhile back. Let’s review the more recent evidence… While the practice of apitherapy dates back 5000+ years, only recently has this potential therapy been scientifically investigated. According to a recent review, bee venom has several peptides as well […]

Continue Reading →