Life Lines by Dr. Dolittle

Tag Archive for ‘health’

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Advancements in veterinary wound healing

Antibiotic-resistant infections are a global concern for both humans and animals. A recent study published in Veterinary Quarterly tested a new way to treat an antibiotic-resistant Pseudomonas aeruginosa wound infection in a Siamese cat, known as “Squeaks”. Squeaks had acquired the infection following multiple surgeries that aimed to treat the cat for injuries after a severe fall from a high-rise. In this study, the veterinary team created a viral phage […]

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What dolphins can teach us about healthy aging

The risk of developing cardiovascular disease increases with aging as arteries can become increasingly stiff and the inner lining, called the endothelium, can become dysfunctional. Postdoctoral fellow Dr. Yara Bernaldo De Quiros Miranda (University of Las Palmas de Gran Canaria) is interested in understanding how bottlenose dolphins, Tursiops truncatus, protect their cardiovascular system during aging. She is currently a visiting scholar at the University of Colorado at Boulder where she […]

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Gut-temperature axis in high altitude deer mice?

Dr. Graham Scott (McMaster University) presented intriguing research at the American Physiology Summit earlier this month in Long Beach, CA. His laboratory has been examining a potential link between the gut microbiome and the ability for deer mice to help regulate body temperature. Deer mice live in high elevations where atmospheric oxygen levels are low. This presents a physiological challenge as they have to use a lot of energy to […]

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Flexible hypoxia tolerance in frogs

In a new study published in The Journal of Neuroscience and presented at the American Physiology Summit earlier this month, graduate student Nikolaus Bueschke, postdoctoral fellow Dr. Lara Amaral-Silva and Dr. Joseph Santin (University of Missouri, Columbia) together with researchers Min Hu and Alvaro Alvarez (University of North Carolina at Greensboro), explored how bullfrogs (Lithobates catesbeianus) emerging from hibernation tolerate hypoxia while they kickstart physiological functions in ice-covered ponds. This […]

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Guest Blog: Fasting as a strategy to build athletic diving capacity

Kaitlin Allen is a graduate student at the University of California, Berkeley where she studies the physiology of elephant seals in the laboratory of Dr. José Pablo Vázquez-Medina. She received the 2024 Dr. Dolittle Travel Award from the Comparative and Evolutionary Physiology section of the American Physiological Society to attend the 2024 American Physiology Summit in Long Beach, CA (April 4-7). Kaitlin prepared this award-winning guest blog entry to describe […]

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Dogs and humans have a lot in common when it comes to brain tumors

The most common type of naturally occurring brain tumor in humans and their feline as well as canine companions are meningiomas. The most aggressive form in humans is Meningioma C (MenG C). Unfortunately, there is currently no treatment available for MenG C and tumors often return even after radiation and surgery. Researchers were curious whether canine meningiomas were similar to human MenG C. In a newly published study, appearing in […]

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Gray wolves living within the Chernobyl Exclusion Zone develop cancer resilience

Like humans, dogs are at risk of spontaneously developing cancer as they age. In fact, cancer is the leading cause of death for dogs (Gardner et al., 2016). Research suggests that dogs may better model cancer than rodents because the disease progression is similar to humans including involvement of the immune system, molecular pathways, variations between animals, tumor resistance to chemotherapy, and metastasis (Gardner et al., 2016). Thus, understanding and […]

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New research shows that muscles in hibernating animals consume energy

Hibernation allows animals to reduce their energy needs during winter, when food may be scarce and high amounts of energy would be required to maintain body temperature. These animals prepare for winter by storing body fat that can be used as fuel during hibernation. Skeletal muscles in particular have high energy needs as they make up nearly half of an animal’s body mass. They also play important roles in regulating […]

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Let’s stop lactate-shaming

As wisely stated in an editorial by Dr. George Brooks, UC Berkeley (2001), “Nature is smarter, and things are more complex than we mortals imagine.” Sure lactate is produced during exercise and is often blamed for causing muscles to fatigue, but there is much more to the story. In fact, research has shown that lactate plays many important physiological roles in the body such as serving as a metabolic fuel […]

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Hydrogen sulfide – the gas we hate to smell, but can’t live without

Although hydrogen sulfide (H2S) is most often associated with manure and the smells of rotten eggs, research has shown it plays important physiological roles. In fact, our bodies actually produce H2S within our cells. Other source of H2S include sulfate-producing bacteria in our gut and dietary intake (such as garlic and cruciferous vegetables). H2S is a member of a group of gasotransmitters, referred to as the ‘reactive species interactome’, that […]

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