Life Lines by Dr. Dolittle

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Tag Archive for ‘hibernation’

It’s getting cold outside…what’s a squirrel to do?

As the weather cools down, animals must find ways to stay warm. This is especially important for small animals as they lose body heat faster than larger animals. One way to stay warm is by increasing your metabolism to create body heat, although this process requires a lot of energy. That can be a problem in areas where food may be scarce in the winter. Although some animals, like the […]

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Tenrecs may shed light on the evolution of body temperature regulation

The common tenrec (Tenrec ecaudatus) just may be a living representative of ancestral placental mammals and they are very interesting when it comes to body temperature regulation and torpor. Torpor is a complex series of physiological changes that reduce an animal’s physical activity as well as heart, breathing and metabolic rates, which also results in decreases in body temperature than can be as low as their surrounding environment. Many mammalian […]

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What can hibernators teach us about obesity? Q&A with Dr. Courtney Kurtz, University of Wisconsin

We are pleased to talk with Dr. Courtney Kurtz, Associate Professor of Biology at the University of Wisconsin, Oshkosh about her research on hibernation and how her research might lead to treatments for obesity. Ground squirrels are a natural model organism for many physiological processes. Can you tell us why you use ground squirrels in your research?  ​Ground squirrels are hibernators.  They spend the majority of the winter in a […]

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Extreme Fasting

While giant pandas roll in horse manure to stay warm in the winter (that’s a different story), other animals spend up to 8 months hibernating to conserve energy during times of reduced food availability and freezing temperatures. During their long winter’s nap, animals such as the Arctic ground squirrel and 13-lined ground squirrel go without food or water while at the same time avoiding muscle wasting – a rather impressive […]

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Rapid switches in metabolism of hibernating animals

  In a new study published in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology, researchers examined how changes in metabolism during torpor are regulated in 13-lined ground squirrels (Ictidomys tridecemlineatus). During hibernation, these animals cycle between bouts of torpor (about 2 weeks each) when their metabolism is reduced by 95% and body temperature can drop to 5degC and short states of interbout euthermia when both temperature […]

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Working towards prolonged spaceflight

Spaceflight has always fascinated me. While long distance spaceflight looks so routine in science fiction shows, the reality is much different as we have yet to conquer the complications surrounding long duration deep-space flight. One issue is how to feed astronauts traveling long distances as we do not yet have replicator technologies. If we did, I would have coffee whenever I wanted it. In a new article published in Physiology, […]

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What do hibernating animals and astronauts have in common?

Well, nothing yet…but imagine the possibilities of human spaceflight if we could put people into a form of stasis? While short term stasis-like states have been used in medical settings, the idea of putting people into stasis to allow long term space travel – without intensive physician oversight, remains a major goal of space agencies and companies like Spaceworks (above). Scientists at the Comparative Physiology meeting considered this very question, […]

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Improving tissue integrity for transplants

Ground squirrels are known for their remarkable ability to tolerate hypothermic conditions. Humans are not. Dr. JingXing Ou (National Institutes of Health) presented an interesting talk that explored using induced pluripotent neuronal stem cells isolated from these mammalian hibernators to improve tissue integrity for organ transplants. By understanding which pathways protected ground squirrel cells from cold-damage, these pathways could be manipulated in human induced pluripotent neuronal stem cells and improve […]

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Dr. Hannah Carey in the spotlight

Congratulations Dr. Hannah Carey, 80th President of the American Physiological Society (2007-2008) and fellow of the American Association for the Advancement of Sciences, which recently interviewed her about her research on hibernation.  Dr. Carey is a comparative physiologist and professor of Comparative Biosciences at the University of Wisconsin School of Veterinary Medicine. Her current research focus is on how the gut microbes of 13-lined ground squirrels change during hibernation. According […]

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Experimental Biology – Day 3

Highlights from today’s sessions included: Norelia Ordonez-Castillo, undergraduate student from Fort Hays State University, presented her research on channel catfish. According to Norelia, these fish can become obese so her research was geared towards trying to find out how their receptor for LDL cholesterol differs from rodents and humans. But what I want to know is whether the obese catfish tastes better… Christine Schwartz, Investigator from University of Wisconsin-La Crosse, studied how […]

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