Life Lines by Dr. Dolittle

Tag Archive for ‘ischemic’

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Physiology on the road: What’s happening in Arizona

The Arizona Physiological Society held their 16th annual meeting this past weekend at Midwestern University in Glendale, Arizona. The Arizona Established Scientist Keynote Speaker was Dr. Christopher Glembotski, Professor of Internal Medicine and Director of the Translational Cardiovascular Research Center at the University of Arizona, Phoenix campus. Ischemic diseases, such as strokes and heart attacks, disrupt the normal functioning of the endoplasmic reticulum, which alters protein production and folding. His […]

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Understanding hypoxia tolerance

Hypoxia associated with ischemic stroke, heart attacks, and solid tumors causes significant pathologies in humans. However, some populations of humans that have lived at high altitudes for generations have adaptations that provide some measures of hypoxia tolerance that may lend insight into treatments for pathological hypoxia in disease states.    Researchers seeking to understand hypoxia tolerance compared the genome of Andean and Ethiopian highlander populations with the genome of Drosophila […]

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