Life Lines by Dr. Dolittle

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Tag Archive for ‘leptin’

Leptin influences mammalian bone development

Leptin is a hormone that was discovered in 1994 and was once heavily studied by researchers who had hoped it might be useful in promoting weight loss.  It is produced by fat cells and signals to the brain whether those fat cells have sufficient energy, at which time it suppresses hunger and thereby promotes weight loss (WebMD; Klok et al., 2007). One of the reasons it failed as a weight […]

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What do frogs and humans have in common?

Leptin is a hormone that signals the brain to suppress appetite in humans. While researchers at the University of Michigan described a similar appetite regulating role for leptin in South African clawed frogs (Xenopus), they also discovered that leptin signals limb development in tadpoles. They suspect that this happens once there are sufficient energy stores to begin the process of metamorphosis. Shalitin and Kiess (2017) also described a role for leptin in skeletal development of children and researchers implicate leptin in […]

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Physiology 2016

I am very excited to report that the American Physiological Society in partnership with The Physiological Society held a joint meeting from July 29-31 in Dublin, Ireland. The keynote lectures were given by Dr. Jerry Friedman from Rockefeller University and Dr. W Jon Lederer from the University of Maryland.   Dr. Friedman spoke about his research on obesity and how genetic factors might play a role. In fact, his team was […]

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