Did you know that your brain is really greedy? It uses about 5.7 kilograms of ATP every day, which is an incredible amount of energy! To keep up with such demand, the brain depends on an adequate supply of oxygen and nutrients, such as glucose. When oxygen or nutrient delivery are limited, like during a heart attack, stroke or in low-oxygen environments, the brain is unable to produce enough ATP […]
In this post, we take a step back in time to feature two legacy articles published in the American Journal of Physiology, written by Jay McClean and Dr. William Howell who studied the physiology of blood clotting. With the 2025 American Physiology Summit taking place in Baltimore, it is only fitting that we take a step back in time to celebrate their important discoveries. Dr. Howell was born in Baltimore, […]
In this Time Machine post, we travel back to 1938 to check out a manuscript on the importance of amino acids in nutrition authored by Dr. William Cumming Rose (1887-1985), professor of biochemistry at the University of Illinois, published in Physiological Reviews. His research on the importance of amino acids in the physiology of an organism culminated in 124 research, review or biographical articles and his receipt of the National […]
We are excited to feature Dr. Frank van Breukelen and his graduate student, Gilbecca Rae Smith, from the University of Las Vegas, Nevada. They presented exciting new research at the 2024 American Physiology Summit examining some little-known functions of the spleen. Q: We often associate the spleen with its ability to filter blood and make white blood cells to fight infections. We don’t often consider the importance of its ability to […]
Humans have occupied high altitude environments for over 10,000 years, allowing ample time for some remarkable adaptations to hypoxia. Such adaptations we have already discussed in people living on the Tibetan Plateau (elevation: 4,500 meters on average) include higher breathing rates combined with lower levels of hemoglobin, the molecule that carries oxygen in the blood, compared to lowland populations, which helps prevent mountain sickness as well as the formation of […]
The Midland Society of Physiological Sciences, comprised of physiologists in Nebraska, South Dakota, and North Dakota is hosting their annual chapter meeting this weekend at the University of South Dakota. Dr. Javier Stern, Distinguished University Professor and Director of the Center for Neuroinflammation and Cardiometabolic Diseases at Georgia State University will present the Keynote lecture on the role of neuropeptides in the hypothalamus of the brain. The title of his […]
Physiologists in Arizona also shared their research this past weekend at the 17th annual Arizona Physiological Society conference held at the University of Arizona in Tucson. 2024 Arizona Physiological Society Established Scientist Keynote Address The Established Scientist Keynote Address was given by Dr. Meredith Hay, Professor and former Executive Vice President and Provost of The University of Arizona in Tucson. Dr. Hay also served as President of the American Physiological […]
In this time machine post, we travel back to 1929 to discuss an article written by Dr. Walter B. Cannon, published in Physiological Reviews. Among other achievements, Dr. Cannon is perhaps best known for being the first to coin the term “homeostasis” and to describe “fight or flight responses” in organisms. As a review article, Dr. Cannon summarized observations made by others about how organisms appear to “maintain their own […]
Antibiotic-resistant infections are a global concern for both humans and animals. A recent study published in Veterinary Quarterly tested a new way to treat an antibiotic-resistant Pseudomonas aeruginosa wound infection in a Siamese cat, known as “Squeaks”. Squeaks had acquired the infection following multiple surgeries that aimed to treat the cat for injuries after a severe fall from a high-rise. In this study, the veterinary team created a viral phage […]
The most common type of naturally occurring brain tumor in humans and their feline as well as canine companions are meningiomas. The most aggressive form in humans is Meningioma C (MenG C). Unfortunately, there is currently no treatment available for MenG C and tumors often return even after radiation and surgery. Researchers were curious whether canine meningiomas were similar to human MenG C. In a newly published study, appearing in […]
Life Lines by Dr. Dolittle 