Life Lines by Dr. Dolittle

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Tag Archive for ‘metabolic’

Extreme tolerance of dehydration stress

Talk about an extreme animal. During the rainy season annual killifish, Austrofundulus limnaeus, lay eggs that are resistant to droughts. This is an important attribute for a fish that lives in temporary pools of water. The stress-resistant embryos within the eggs literally shut down their metabolism to survive months – possibly years without water. For many fish, exposure to air (and oxygen) can cause profound oxidative stress. Remarkably, this is […]

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Cholesterol levels in tissues change during hypoxia in naked mole rats

Naked mole rats are rather famous from a physiological perspective for their amazing ability to live in hypoxic conditions. They do so in part by reducing their metabolic rate. In fact, researchers at the University of Ottawa in Canada showed that reducing environmental oxygen levels to 11% resulted in a 34% decrease in the animal’s metabolic rate. Studies of hypoxia-tolerant goldfish show that the animals respond to hypoxia challenges by […]

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