Life Lines by Dr. Dolittle

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Tag Archive for ‘Physiological Reviews’

The physiology of bad taste

Ever wonder how humans and other animals evolved the ability to detect foods that can potentially harm us? A recent article published in Physiological Reviews, explains the physiology behind why certain foods taste bad. The act of tasting is very complex and includes receptors in our mouths that can detect specific chemicals in our food and prepare our digestive system to receive the food and, as anyone with a cold knows, […]

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Zebrafish as models for human disease and drug development

  Who would have thought tiny fish could lead to big advances in medicine? Zebrafish (Danio rerio) and mammals have similar anatomy and physiology of the brain, eyes, gut, and cardiovascular systems. Some of the reasons why these fish are good models to understand cardiovascular physiology were recently explored in a new article published in Physiological Reviews. Animal models are used in research that seeks to understand both normal physiological mechanisms as […]

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Oh, the many things estrogens can do…in males

I came across an article published in Physiological Reviews with a title so irresistible (Estrogens in Male Physiology), I just had to read it. While I knew that males have estrogen, this article impressed me with the numerous things estrogens are associated with, some of which were new to me and highlight how important estrogens are to male reproductive and non-reproductive physiology. As early as the 1930’s researchers discovered that stallions had high […]

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Secrets to Longevity

A new article published in Physiological Reviews compared some remarkable similarities and differences between naked mole rats and humans. Both are relatively long-lived, highly social and have low natural selection pressures. But, this is about all they have in common. While humans are prone to developing age-related cancer, diabetes, heart disease and dementias, naked mole rats are rather resistant to these diseases. Instead, naked mole rats appear to maintain a youthful […]

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