Life Lines by Dr. Dolittle

Sponsored by the American Physiological Society

Tag Archive for ‘virus’

Mice have special ‘jumping genes’ that help them survive viral infections

Researchers at the University of New South Wales (UNSW), Sydney discovered a ‘jumping gene’ that prevents the immune system of mice from overreacting to a viral infection. Jumping genes are movable nucleic acids, or transposable elements, that make up nearly 2/3 of the genome in mammals. They help regulate the expression of genes. Some transposable elements in the genome are new and some originated in ancient times. In the new […]

Continue Reading →

Dolphins can develop similar neurological diseases as humans

I am pretty sure most people would agree that dolphins are pretty smart. But did you know that they may develop similar neurological conditions as humans? I read an interesting article published in Drug Target Review exploring how dolphins that have washed up on beaches may help us understand neurological diseases like Alzheimer’s as well as responses to viral infections. For example, Dolphin morbillivirus (DMV) is a virus similar to […]

Continue Reading →

Resisting bird flu

I just read an interesting article from the Max Delbruck Center for Molecular Medicine in the Helmholtz Association that explained why human cells are typically quite resistant to bird flu. Bird flu (H5N1, H7N9, H5N6) does not readily spread between infected humans. In fact, most outbreaks involve only a handful to a few hundred individuals. But, on occasion, the infection can spread more easily leading to a pandemic. New research […]

Continue Reading →

Viral defenses are encoded in their genes, but not ours

Through the course of evolution vertebrates have apparently lost their gene-encoded viral defense mechanisms. These ancient defenses allow plants and insects to silence the expression of certain genes by using what is known as RNA interference. This natural defense system can be manipulated to create genetically modified crops that resist certain infections. However, a new study by researchers from the University of Leuven in Belgium examined over 40 organisms in […]

Continue Reading →

Genetically-modified virus stops Alzheimer’s disease

Check out this video from Reuters (via YouTube). It summarizes an exciting study from researchers at Imperial College London who were able to stop the progression of Alzheimer’s disease in mice by administering a modified virus to the animals. The virus worked by preventing the formation of the characteristic amyloid plaques that are responsible for causing damage to neurons in the brain. Importantly, the virus did not result in loss […]

Continue Reading →