Among mammals, humans are known for having exceptional endurance. For example, persistence hunters can run for 2-5 hours to wear out their prey, while marathoners routinely run ~4.5 hours on average (Schulte et al., 2015). Sure, a cheetah can run fast, but it can’t run as long as a human. How did humans develop such exceptional endurance? When vertebrates moved to dry land, they needed to develop lungs to extract […]
Humans have occupied high altitude environments for over 10,000 years, allowing ample time for some remarkable adaptations to hypoxia. Such adaptations we have already discussed in people living on the Tibetan Plateau (elevation: 4,500 meters on average) include higher breathing rates combined with lower levels of hemoglobin, the molecule that carries oxygen in the blood, compared to lowland populations, which helps prevent mountain sickness as well as the formation of […]
Physiologists in Arizona also shared their research this past weekend at the 17th annual Arizona Physiological Society conference held at the University of Arizona in Tucson. 2024 Arizona Physiological Society Established Scientist Keynote Address The Established Scientist Keynote Address was given by Dr. Meredith Hay, Professor and former Executive Vice President and Provost of The University of Arizona in Tucson. Dr. Hay also served as President of the American Physiological […]
In this time machine post, we travel back to 1929 to discuss an article written by Dr. Walter B. Cannon, published in Physiological Reviews. Among other achievements, Dr. Cannon is perhaps best known for being the first to coin the term “homeostasis” and to describe “fight or flight responses” in organisms. As a review article, Dr. Cannon summarized observations made by others about how organisms appear to “maintain their own […]
Programmed cell death, otherwise known as apoptosis, is an important physiological process that allows the body to get rid of cells that are no longer needed or are damaged. These functions help foster normal growth and development as well as prevent cancer. Apoptosis is a highly regulated process that involves various caspase enzymes, with caspase-3 being among the “executioner” enzymes responsible for the final stages of apoptosis and ultimate cellular […]
Life Lines by Dr. Dolittle 