Life Lines by Dr. Dolittle

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Archive for May 2019

Working towards prolonged spaceflight

Spaceflight has always fascinated me. While long distance spaceflight looks so routine in science fiction shows, the reality is much different as we have yet to conquer the complications surrounding long duration deep-space flight. One issue is how to feed astronauts traveling long distances as we do not yet have replicator technologies. If we did, I would have coffee whenever I wanted it. In a new article published in Physiology, […]

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Growth restriction in utero increases risk for developing insulin resistance

  A new study published in theĀ American Journal of Physiology – Regulatory, Integrative and Comparative Physiology, explored how restricted growth of a fetus during pregnancy can lead to insulin resistance later in life. They studied this risk factor in guinea pigs as larger litter sizes are known to restrict the growth of developing fetuses. Findings from the study showed that neonatal guinea pigs grow rapidly after birth to compensate for […]

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Lactate directly increases breathing

Hypoxic environments increase ventilation in animals. This helps to bring in more oxygen when environmental levels may be limited. With limited oxygen availability, the body turns to anaerobic metabolism, resulting in the production of lactate ions. These ions are known to indirectly stimulate breathing by lowering blood pH and were more recently discovered to directly stimulate the carotid body to increase breathing. For this reason, lactate ions are thought to […]

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