Life Lines by Dr. Dolittle

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Aging

Infertility is not an issue for naked mole rats

Naked mole-rats have attracted the attention of scientists once again. Not only do they live very long lives (30+ years), while typically avoiding cancer, females remain fertile their whole life. Unlocking their secrets to avoiding menopause may lead to new ways to treat infertility. New research has identified their tricks for lifelong fertility. It turns out that female naked mole-rats have 1.5 million egg cells (oocytes) when they are born, […]

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Considering a cranberry side dish for Thanksgiving? New study shows regular consumption may lower cholesterol and prevent memory loss

Okay, I’ll admit this blog entry has nothing really to do with comparative physiology. I just happen to really like eating cranberry sauce at Thanksgiving and was curious about the benefits of eating cranberries more often. Like many other berries, cranberries are a super-fruit rich in polyphenols and antioxidants that are associated with protecting brain health with aging. On their own they are rather bitter due to the high amounts […]

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Arizona physiologists gathered recently for their annual meeting

The Arizona Physiological Society, a chapter of the American Physiological Society, hosted their 15th annual scientific meeting this past weekend! Here are some highlights… The Keynote Address was presented by Dr. Harold D Schultz, Professor in the Department of Cellular and Integrative Physiology at the University of Nebraska. His talk focused on the physiology of heart failure and how the nervous system regulates blood pressure. This year’s Arizona Distinguished Physiologist […]

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Physiology in the Midlands

Fall is an exciting time as many of the chapters of the American Physiological Society host regional conferences. The Midlands Society of Physiological Sciences hosted their annual meeting earlier this month. Here are some highlights from their meeting. Symposia highlights: The meeting was kicked off by a Keynote Lecture presented by Dr. David A Kass from Johns Hopkins University who presented his research on obesity and heart failure. Here is […]

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Aging and Immortality

Have you ever heard of the ‘immortal’ jellyfish, Turritopsis dohrnii? These tiny creatures (about 4.5 mm) are aptly named for their ability to essentially live forever. According to the Natural History Museum, when these jellyfish are damaged, they can actually revert to a prior life cycle as a polyp and become an adult jellyfish (aka, medusa) all over again. This process is called transdifferentiation. Check out this video from the […]

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Causes and consequences of stiff arteries

In a new review article published in Physiology, researchers speculate that arterial stiffness in middle-aged adults may actually be the body’s way of trying to compensate for widening of the blood vessel walls as we age. But that benefit turns into a risk with aging as it increases the flow of blood into organs like the brain, kidney, and heart and damages the small blood vessels in those organs. Interestingly, […]

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Domestic zebrafish are less plastic

Zebrafish have been used in medical research since at least the 1970’s as their anatomy, physiology, as well as genetics are similar to humans. Other advantages to studying zebrafish is that they are inexpensive to raise, and they reproduce well in captivity. The ability to adjust one’s physiology in response to varying environments is called plasticity. An organism may encounter any number of environmental fluctuations (light/dark, temperatures, predation risk, noise, […]

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Buoyancy and Balance

Existing species of coelacanths (pictured above) are descendants of a group of fish that existed about 410 million years ago, during the early Devonian period. They can be found in the Western Indian Ocean off the coast of Indonesia. These fish are really interesting because they have very low metabolic rates. In fact, their metabolism is among the lowest of any other existing vertebrate. Even sloths are jealous of their […]

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Geriatric bees

Jacob Pithan, a graduate student in the laboratory of Dr. Kendra Greenlee (North Dakota State University), presented their research examining how aging affects exercise performance as well as oxidative health at last month’s Experimental Biology conference in Philadelphia. The oxidative stress theory of aging postulates that aging results from an overproduction of free radicals along with a decrease in antioxidants that can scavenge them. The problem with free radicals is […]

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EB 2022: Modeling human diseases and healthy aging

I sat through a very interesting session at this year’s Experimental Biology conference called, “The Power of Comparative Models for Accelerating Translational Healthspan Research: Underutilized Lab Animals, Companion Pets, Old World Monkeys, and Pumas.” While the title seems to capture the general idea of the symposium, I thought I would share a bit more information about the presenters and their exciting research. Dr. Karyn Hamilton from Colorado State University presented […]

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