Life Lines by Dr. Dolittle

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Tag Archive for ‘carbon monoxide’

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Experimental Biology 2021: Q&A with Dr. Michael Tift and Anna Pearson

We are delighted to speak with Anna Pearson (MS student) and her mentor Dr. Michael Tift, Assistant Professor at the University of North Carolina – Wilmington. Anna presented her research “First report of red blood cell lifespan in a marine mammal: An insight into endogenous carbon monoxide (CO) production” at the 2021 Experimental Biology conference last month. What made you interested in studying red blood cells in dolphins?Dr. Tift became interested […]

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Hypoxia and anoxia and reoxygenation, Oh my!

There are many examples of animals that can naturally tolerate hypoxic and anoxic conditions without exhibiting pathologies associated with reoxygenation. Here are a few examples from this year’s conference: Dr. Anthony Signore (University of Nebraska) spoke about how some hypoxia tolerant animals can use carbon monoxide, you know that gas we think of as poisonous, to improve oxygen binding to hemoglobin in hypoxic conditions. Well known for their ability to […]

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Experimental Biology 2017 – Day 5

Here are the highlights from the final day of the meeting: Carbon monoxide (CO) is not all that bad: Michael Tift, graduate student at Scripps Institute of Oceanography, described how the body naturally produces CO when red blood cells are broken down and CO can actually be protective against inflammation at low doses. His research was focused on measuring whether species that have more hemoglobin (from living in hypoxic environments) also have […]

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Carbon monoxide lowers breathing rate in fish too

  We tend to think of carbon monoxide (CO) only in terms of being a poisonous gas. The reason for its toxicity is due to its ability to bind really tightly to our hemoglobin molecules, which prevents oxygen from being able to bind. In mammals, CO also decrease breathing rate. As you can imagine, it is a pretty terrible gas to breath in when you are a species dependent on hemoglobin for delivery […]

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