Life Lines by Dr. Dolittle

Sponsored by the American Physiological Society

Hypoxia and anoxia and reoxygenation, Oh my!

Comparative Mastehead 2018

There are many examples of animals that can naturally tolerate hypoxic and anoxic conditions without exhibiting pathologies associated with reoxygenation. Here are a few examples from this year’s conference:

Dr. Anthony Signore (University of Nebraska) spoke about how some hypoxia tolerant animals can use carbon monoxide, you know that gas we think of as poisonous, to improve oxygen binding to hemoglobin in hypoxic conditions.

Image result for turtle skeleton wikimedia

Image of a turtle skeleton by Felipe Oliveira Ribas via Wikimedia Commons

Well known for their ability to regulate blood calcium concentrations, Dr. Daniel Warren (St. Louis University) presented a poster yesterday describing how anoxia-tolerant painted turtles may also use their skeletons to help buffer the pH of their blood by preventing acidosis resulting from lactate metabolism.

Image result for drosophila

Photo by Muhammad Mahdi Karim from Wikimedia Commons

Dr. Jacob Campbell (USDA-ARS) presented data showing that anoxia tolerance varies across lifespan in drosophila with adults more tolerant than larvae.


Image of a crucian carp by Viridiflavus via Wikimedia Commons 

Dr. Sjannie Lefevre (University of Oslo) presented research showing that, athough crucian carp (Carassius carassius) can survive anoxic conditions for a period of several months, these animals are remarkably resistant to damage caused by tissue reoxygenation.

Categories: Environment, Extreme Animals, Hibernation and Hypoxia, Physiology on the Road

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