Life Lines by Dr. Dolittle

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Tag Archive for ‘Environment’

Anoxia tolerance in goldfish

The reason mammals are not very good at tolerating hypoxic (i.e. low oxygen) environments, is because the brain relies heavily on oxygen for metabolism. It is so stingy, it uses about 20% of the oxygen in the body to make ATP. Without oxygen, the brain has to rely on glycolysis to make ATP and this process is not good at meeting the energy requirements of the neurons, ultimately resulting in […]

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Nature’s architects

Nature has already solved many problems that doctors, researchers, and architects are still trying to solve for humans. For example, some of our prior posts have talked about how some animals are resistant to developing cancer: Elephants Tasmanian devils Naked mole rats Other animals have developed special nano antibodies (nanobodies) to fight disease. Llamas While several are tolerant of very low oxygen levels in the environment, others are champions of […]

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Cholesterol levels in tissues change during hypoxia in naked mole rats

Naked mole rats are rather famous from a physiological perspective for their amazing ability to live in hypoxic conditions. They do so in part by reducing their metabolic rate. In fact, researchers at the University of Ottawa in Canada showed that reducing environmental oxygen levels to 11% resulted in a 34% decrease in the animal’s metabolic rate. Studies of hypoxia-tolerant goldfish show that the animals respond to hypoxia challenges by […]

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How some fish may compensate for low environmental oxygen

     Adult fish rely on gills to extract oxygen from the surrounding water. Larval fish, on the other hand, do not have well-developed gills and instead rely primarily on gas exchange across their skin.      In a new study published in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology, researchers examined whether larval fish could use their pectoral fins to increase the flow of water […]

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New study shows mussels are “hot and bothered”

Freshwater organisms are especially vulnerable to environmental changes as they are exposed to both atmospheric changes as well as run-off from nearby cities; in particular, rising temperatures and increasing carbon dioxide levels from both natural factors (rainfall, geology, etc) as well as human influence (deforestatin, agriculture, urbanization). For example, studies of rivers around the world have found that carbon dioxide levels vary from 647 – 38,000 µatm. Higher levels are […]

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Pigeons in the lead mine?

With reported lead poisonings in cities such as Flint Michigan, methods to detect risk of exposure are desperately needed. Since pigeons live in close proximity to humans, could pigeons be the ‘canary in the lead mine’? Researchers at Columbia University in New York City measured the concentrations of lead in the blood of 825 ill or injured feral pigeons to determine whether the animals could serve as bioindicators of levels in the environment. Their results were published […]

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