Life Lines by Dr. Dolittle

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Tag Archive for ‘high altitude’

Life at the top

Moving to high altitude requires a bit of an adjustment. One of the ways our bodies adjust to the low levels of oxygen is by making more red blood cells, which are responsible for transporting oxygen in the body. More red blood cells means that our blood can pick up more oxygen. If this process continues unchecked, however, it can lead to chronic mountain sickness, also known as Monge’s Disease. […]

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Featuring: Ohio Physiological Society

This week we are featuring the Ohio Physiological Society. They held their 35th annual meeting September 17-18, 2021. The Ohio Physiological Society is a chapter of the American Physiological Society that was founded in 1986 and brings together physiologists from across the state. Dr. Cynthia Beall, PhD, Distinguished University Professor and Sara Idell Pyle Professor of Anthropology as well as Co-Director of the Center for Research on Tibet at Case […]

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High altitude survival and adaptation

Life at high altitude presents unique physiological challenges for organisms that were explored in a recent review published in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology. For placental mammals, offspring born at high altitude (>2500 m above sea level) typically weigh less at birth compared to lowland animals. Fetal growth restriction is problematic as it is associated with long-term health risks and reduced survival. It is […]

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Surviving the cold

The ability to regulate body temperature is critical for animals. This is especially true for small mammals as they have a larger surface area resulting in more heat loss to the environment than larger animals. Animals that stay active during the winter likewise have to spend more energy to stay warm. To do this well, they need to balance heat loss with heat generation through shivering as well as non-shivering […]

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Physiology in Arizona

The Arizona Physiological Society will be hosting their 12th annual meeting Friday and Saturday on the Arizona State University campus. Physiologists from all over the state will be meeting to talk about a variety of topics ranging from comparative physiology to clinical trials. The 2019 Arizona Distinguished Lecturer is Dr. Ralph Fregosi from the University of Arizona in Tucson who specializes in respiratory physiology. The Keynote speaker will be Dr. […]

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Remarkable hypoxia and cold tolerance of rodents native to the Tibetan plateau

The plateau zokor (Eospalax baileyi) is an underground dwelling rodent species native to the Tibetan plateau (2000-4200 meters in elevation). A new study published in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology explored how these animals were adapted to extract oxygen from an environment with very low levels (83-88% of atmospheric). Hemoglobin molecules found in red blood cells are responsible for binding oxygen and transporting it to tissues […]

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High altitude deer mice have less stress?

Animals that live at high altitude have evolved a number of physiological adaptations to deal with the low atmospheric oxygen concentrations (hypoxia). For low altitude acclimated animals, short exposures to high altitude results in activation of the sympathetic nervous system (i.e. the fight or flight response). This is a good thing because activation of this system results in more blood flow, especially to the heart and brain to help protect oxygen […]

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How Animals Deal with Stress

  Victor Zhang (Graduate Student working with Dr. Loren Buck at Northern Arizona University) gave an interesting talk on his research to measure stress and activity patterns in free living arctic ground squirrels. They found overall that females were less stressed than males although stress levels and activity varied during lactation. I think some human mothers can agree with those observations. Oliver Wearing (Graduate student working with Dr. Graham Scott […]

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Experimental Biology – Day 3

Highlights from today’s sessions included: Norelia Ordonez-Castillo, undergraduate student from Fort Hays State University, presented her research on channel catfish. According to Norelia, these fish can become obese so her research was geared towards trying to find out how their receptor for LDL cholesterol differs from rodents and humans. But what I want to know is whether the obese catfish tastes better… Christine Schwartz, Investigator from University of Wisconsin-La Crosse, studied how […]

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