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Tag Archive for ‘American Journal of Physiology’

Study examines link between sleep apnea and cancer

A recent review published in the¬†American Journal of Physiology – Regulatory, Integrative and Comparative Physiology¬†explored the link between sleep apnea and cancer (4). More and more people are living with sleep apnea. In fact, current estimates indicate that up to 24% of men as well as up to 5% of women have obstructive sleep apnea (4). Individuals with sleep apnea experience repeated cycles of low oxygen (hypoxia) and reoxygenation throughout […]

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Extreme fasting

  Northern Elephant seals (Mirounga angustirostris) are pretty extreme animals, at least when it comes to fasting. Pups nurse for about 1 month, during which time they greatly increase their body fat. After nursing, they typically fast for up to 3 months. A new study was designed to explore how their adipose (fat) tissue changes after this prolonged fast. Researchers at the University of California at Merced were able to […]

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Leptin influences mammalian bone development

Leptin is a hormone that was discovered in 1994 and was once heavily studied by researchers who had hoped it might be useful in promoting weight loss.  It is produced by fat cells and signals to the brain whether those fat cells have sufficient energy, at which time it suppresses hunger and thereby promotes weight loss (WebMD; Klok et al., 2007). One of the reasons it failed as a weight […]

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Caffeine redemption

Sometimes caffeine gets bad rap. But, not all caffeine drinks are created equal and certainly there are health issues related to over-consumption. But, as an avid coffee drinker, I’d like to think there are some benefits to my favorite morning treat. A recent article published in American Journal of Physiology – Endocrinology and Metabolism highlighted some of the health benefits of caffeine. Thank you AJP! Obesity is a complicated condition that can […]

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Pediatric obesity in marmoset monkeys begins in the womb

A new review article published in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology explored an interesting question: how do prenatal experiences along with the intrauterine environment impact the future development of pediatric and adult obesity in animals? Common marmosets (Callithrix jacchus) are New World monkeys that can spontaneously develop obesity early in life when living in captivity with high food availability and relatively low physical activity. Similar to […]

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Understanding stress-induced miscarriage and premature delivery

  Stress during late pregnancy may result in premature delivery or stillbirth. A new study of pregnant Rambouillet cross ewes, published in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology, was designed to understand why lambs succumb to stress late in pregnancy. They found that while arterial blood pressure and heart rates were normal during late gestation (final 2 weeks before birth) in fetuses from pregnant ewes with elevated stress hormones, fetal heart rate and aortic blood pressure declined on the day […]

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Tapeworms treat IBD?

Okay, I realize this is not a comparative physiology topic. But after reading this article, I just had to share it. A new study published in American Journal of Physiology – Gastrointestinal and Liver Physiology presented data suggesting that parasitic worms may help treat or even prevent inflammatory bowl disease (IBD) in children. IBD is a condition characterized by inflammation in the gut that can lead to symptoms such as diarrhea […]

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Chronic stress causes muscle loss

Researchers have known that chronic stress has many negative health effects that can impair normal growth. The impact of stress on skeletal muscle specifically is less understood. For this reason, researchers at Universidad Andres Bello in Chile explored the effects of stress induced by overcrowding in fine flounders (Paralichthys adspersus). Their results were published this month in American Journal of Physiology – Regulatory, Integrative and Comparative Physiology.  After just four weeks of […]

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How Ossabaw Island swine are helping us understand obesity and diabetes

         Ossabaw Island off the coast of Georgia (United States) is home to feral swine brought over by early Spanish explorers. In relative isolation on the island, with the exception of the introduction of a Hampshire pig, the Ossabaw pigs have become genetically distinct from those living on the mainland. Ossabaw pigs are prone to obesity and are the only miniature pigs known to develop type 2 […]

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Importance of diet to the physiology of farm-raised fish

Image of a fish farm by Vera Kratochvil [Public domain], via Wikimedia Commons Fish farming, i.e. aquaculture, has increased about 6.2% between the years 2000-2012, according to the Food and Agriculture Organization of the United Nations. Fish farms are highly dependent on fish meal as well as fish oil as nutrients for the growing fish. Although rates of farming have increased, the supply of fish meal and oil are predicted […]

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