Life Lines by Dr. Dolittle

Sponsored by the American Physiological Society

Tag Archive for ‘growth’

Researchers explore why fetuses that experienced intrauterine growth restriction have smaller muscles

We have talked several times about the long-lasting issues related to growth restriction of a fetus during pregnancy: Intrauterine growth restriction increases risk of cardiovascular disease as adults Intrauterine growth restriction increases risk of insulin resistance as adults It can also result in offspring that have smaller muscles. New research published in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology suggests this may be due to adaptations to […]

Continue Reading →

A mother’s diet can have a lasting impact on offspring

A new study published in Physiological Reports provides evidence that a mother’s diet during pregnancy could have lasting impacts on her offspring’s bone development and later risk of osteoporosis. Osteoporosis is characterized by a loss of trabecular (spongy) bone leading to increased risk for developing bone fractures.  The researchers discovered this relationship while studying female microswine that were consuming a diet containing only 1% protein late in their pregnancy and for […]

Continue Reading →

Growth restriction in utero increases risk for developing insulin resistance

  A new study published in the American Journal of Physiology – Regulatory, Integrative and Comparative Physiology, explored how restricted growth of a fetus during pregnancy can lead to insulin resistance later in life. They studied this risk factor in guinea pigs as larger litter sizes are known to restrict the growth of developing fetuses. Findings from the study showed that neonatal guinea pigs grow rapidly after birth to compensate for […]

Continue Reading →

Leptin influences mammalian bone development

Leptin is a hormone that was discovered in 1994 and was once heavily studied by researchers who had hoped it might be useful in promoting weight loss.  It is produced by fat cells and signals to the brain whether those fat cells have sufficient energy, at which time it suppresses hunger and thereby promotes weight loss (WebMD; Klok et al., 2007). One of the reasons it failed as a weight […]

Continue Reading →